Scarring is a major clinical problem. Burns, traumatic injuries, and surgical procedures can give rise to exuberant scars that can cause permanent cosmetic and functional problems.
BAPSCARCARE is a silicone scar therapy. Silicone therapy has been the most widely accepted scar treatment by professionals worldwide for over 20 years and has been scientifically proven to be the best. Silicones are known for the excellent tolerance and water vapor permeability of the skin. In addition, silicones are impermeable and protect the scar against bacteria.
Various scientific studies with silicone therapy show an effect on both the treatment of scars and the prevention of scars. The studies provide evidence of the effect of silicone on:
Abnormal collagen that can make a scar stiffer and harder
Contracts faster which can cause pain and restriction of movement
Limited elastin making the skin less supple and elastic
Thin dermis with less or limited skin properties
Hypertrophic and keloid scars are abnormal reactions of the body to wound closure. The excessive growth of connective tissue is a response to trauma, inflammation, surgery, or burn. Many factors can affect hypertrophy or keloid, namely:
Genetic predisposition
Race
Age
Type of trauma
The exact course of a scar is still unknown, but a combination of biological, genetic, celluary, immunological and endocrinological factors probably play a role.
Silicone gel: a new treatment for burn scars and contractures.
Author(s): Perkins K, Davey RB, Wallis KA.
Publication: Burns, including thermal injury. 1983; 9(3):201-4.
Topical silicone gel: a new treatment for hypertrophic scars.
Author(s): Ahn ST, Monafo WW, Mustoe TA.
Publication: Surgery. 1989; 106(4):781-6; discussion 6-7.
Gel sheeting in the management of hypertrophic scarring.
Author(s): Carney SA, Cason CG, Gowar JP, Stevenson JH, McNee J, Groves AR, et al.
Publication: Burns : journal of the International Society for Burn Injuries. 1994; 20(2):163-7.
A comparison of Sil-K and Epiderm in scar management.
Author(s): Lee SM, Ngim CK, Chan YY, Ho MJ.
Publication: Burns : journal of the International Society for Burn Injuries. 1996; 22(6):483-7.
Silicone versus nonsilicone gel dressings: a controlled trial.
Author(s): de Oliveira GV, Nunes TA, Magna LA, Cintra ML, Kitten GT, Zarpellon S, et al.
Publication: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al]. 2001; 27(8):721-6.
Evaluation of a self-adherent soft silicone dressing for the treatment of hypertrophic postoperative scars.
Author(s): Majan JI.
Publication: Journal of wound care. 2006; 15(5):193-6.
A prospective randomized clinical trial to investigate the effect of silicone gel sheeting on post-traumatic hypertrophic scar among the Chinese population.
Author(s): Li-Tsang CWP, Lau JCM, Choi J, Chan CCC, Jianan L.
Publication: Burns : journal of the International Society for Burn Injuries. 2006; 32(6):678-83.
Evidence that use of a silicone gel sheet increases range of motion over burn wound contractures.
Author(s): Wessling N, Ehleben CM, Chapman V, May SR, Still JM, Jr.
Publication: The Journal of burn care & rehabilitation. 1985; 6(6):503-5.
Silicone gel in scar treatment.
Author(s): Quinn KJ
Publication: Burns, including thermal injury. 1987; 13 Suppl:S33-40.
Effectiveness of silastic sheet coverage in the treatment of scar keloid (hypertrophic scar).
Author(s): Ohmori S.
Publication:Aesthetic plastic surgery. 1988; 12(2):95-9.
Effects of lipopolysaccharide on intestinal injury; potential role of nitric oxide and lipid peroxidation.
Author(s): Mercer DW, Smith GS, Cross JM, Russell DH, Chang L, Cacioppo J.
Publication: The Journal of surgical research. 1996; 63(1):185-92.
Topical silicone gel for the prevention and treatment of hypertrophic scar.
Author(s): Ahn ST, Monafo WW, Mustoe TA.
Publication: Archives of surgery. 1991; 126(4):499-504.
Topical silicone gel sheeting in the treatment of hypertrophic scars and keloids. A dermatologic experience.
Author(s): Gold MH.
Publication: The Journal of dermatologic surgery and oncology. 1993; 19(10):912-6.
Silicone Occlusive Sheeting (Sos) in the Management of Hypertrophic and Keloid Scarring, Including the Possible Mode of Action of Silicone, by Static Electricity.
Author(s): Hirshowitz B, Ullmann Y, Harshai Y, Vilenski A, Peled IJ.
Publication: Eur J Plast Surg. 1993; 16(1):5-9.
A controlled clinical trial of topical silicone gel sheeting in the treatment of hypertrophic scars and keloids.
Author(s): Gold MH.
Publication: Journal of the American Academy of Dermatology. 1994; 30(3):506-7.
Silicone gel sheeting for the prevention and management of evolving hypertrophic and keloid scars.
Author(s): Fulton JE, Jr.
Publication: Dermatologic surgery : official publication for American Society for
Dermatologic Surgery [et al]. 1995; 21(11):947-51.
Comparison of a silicone gel-filled cushion and silicon gel sheeting for the treatment of hypertrophic or keloid scars.
Author(s): Berman B, Flores F.
Publication: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al]. 1999; 25(6):484-6.
Silicone gel sheets relieve pain and pruritus with clinical improvement of keloid: possible target of mast cells.
Author(s): Eishi K, Bae SJ, Ogawa F, Hamasaki Y, Shimizu K, Katayama I.
Publication: The Journal of dermatological treatment. 2003; 14(4):248-52.
Preliminary evaluation of the efficacy of Dermatix silicone gel in the reduction of scar elevation and pigmentation.
Author(s): Murison M, James W.
Publication: J Plast Reconstr Aes. 2006; 59(4):437-9.
The efficacy of topical silicone gel elastomers in the treatment of hypertrophic scars, keloid scars, and post-laser exfoliation erythema.
Author(s): Chernoff WG, Cramer H, Su-Huang S.
Publication: Aesthetic plastic surgery. 2007; 31(5):495-500.
Comparison of efficacy of silicone gel, silicone gel sheeting, and topical onion extract including heparin and allantoin for the treatment of postburn hypertrophic scars.
Author(s): Karagoz H, Yuksel F, Ulkur E, Evinc R.
Publication: Burns : journal of the International Society for Burn Injuries. 2009; 35(8):1097-103.
Aesthetic Effect of Silicone Gel on Surgical Scars in Asians.
Author(s): Rhee SH, Koh SH, Lee DW, Park BY, Kim YO
Publication: J Craniofac Surg. 2010; 21(3):706-10.
Efficacy of the combination of herbal extracts and a silicone derivative in the treatment of hypertrophic scar formation after burn injury.
Author(s): Muangman P, Aramwit P, Palapinyo S, Opasanon S, Chuangsuwanich A
Publication: Afr J Pharm Pharmaco. 2011; 5(3):442-6.
The efficacy of topical silicone gel elastomers in the treatment of hypertrophic scars, keloid scars, and post-laser exfoliation erythema.
Author(s): Chernoff WG, Cramer H, Su-Huang S
Publication: Aesthetic plastic surgery. 2007; 31(5):495-500.
A randomized, placebo- controlled, double-blind, prospective clinical trial of silicone gel in prevention of hypertrophic scar development in median sternotomy wound.
Author(s): Chan KY, Lau CL, Adeeb SM, Somasundaram S, Nasir-Zahari M
Publication: Plastic and reconstructive surgery. 2005; 116(4):1013-20.
Clinical evaluation of a new self-drying silicone gel in the treatment of scars: a preliminary report.
Author(s): Signorini M, Clementoni MT
Publication: Aesthetic plastic surgery. 2007; 31(2):183-7.
The use of silicone gel in the treatment of fresh surgical scars: a randomized study.
Author(s): de Giorgi V, Sestini S, Mannone F, Papi F, Alfaioli B, Gori A, Lotti T.
Publication: Clinical and experimental dermatology. 2009; 34(6):688-93.
Evolution of silicone therapy and mechanism of action in scar management.
Author(s): Mustoe TA.
Publication: Aesthetic plastic surgery. 2008; 32(1):82-92.
International clinical recommendations on scar management.
Author(s): Mustoe TA, Cooter RD, Gold MH, Hobbs FD, Ramelet AA, Shakespeare PG, et al.
Publication: Plastic and reconstructive surgery. 2002; 110(2):560-71.
Silicone-based scar therapy: a review of the literature.
Author(s): Stavrou D, Weissman O, Winkler E, Yankelson L, Millet E, Mushin OP, et al.
Publication: Aesthetic plastic surgery. 2010; 34(5):646-51.